APoGI for the Haemoglobin Disorders

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Implications for a Child when One Partner carries Haemoglobin Lepore thalassaemia and the Other does not carry any Haemoglobin disorder

There is no particular problem for this couple. This combination cannot cause a serious inherited anaemia.

Partner who carries haemoglobin Lepore thalassaemia			Partner who is NOT a carrier

Not a carrier	Carrier of haemoglobin Lepore thalassaemia	Not a carrier	Carrier of haemoglobin Lepore thalassaemia

In each pregnancy there are two possibilities:

The child may not carry any haemoglobin disorder.
The child may carry haemoglobin Lepore thalassaemia. This is harmless.

This couple has the same chance of a healthy family as other couples do.

When the children grow up...

... they should have blood test to see if they have inherited haemoglobin Lepore thalassaemia. If they have, their partner should have a test "for haemoglobin disorders". It is important to remember this for the future.

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These documents are part of the APoGI May 1998 (Evaluation) Release and are made available subject to the APoGI Disclaimers covering usage, distribution and copying.

Problems or further enquiries to APoGI@chime.ucl.ac.uk or the APoGI Contacts