APoGI for the Haemoglobin Disorders

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Implications for a Child when One Partner carries Delta-beta thalassaemia and the Other carries Haemoglobin D (type unknown)

There is no particular problem for this couple. This combination cannot cause a serious inherited anaemia in their children.

Partner who carries delta-beta thalassaemia			Partner who carries haemoglobin D (type unknown)

Not a carrier	Carrier of delta-beta thalassaemia	Carrier of heamogobin D (type unknown)	Child who carries both delta-beta thalassaemia and haemoglobin D (type unknown)

In each pregnancy, there are four possibilities:

The child may not carry any haemoglobin disorder.
The child may carry delta-beta thalassaemia. This is harmless.
The child may carry haemoglobin D. This is harmless.
The child may inherit delta-beta thalassaemia from one parent and Haemoglobin D from the other. This is harmless.

This couple has the same chance of a healthy family as other couples do.

When the children grow up...

... they should have blood test to see if they have inherited delta-beta thalassaemia or haemoglobin D. If they have, their partner should have a test "for haemoglobin disorders". It is important to remember this for the future.

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These documents are part of the APoGI May 1998 (Evaluation) Release and are made available subject to the APoGI Disclaimers covering usage, distribution and copying.

Problems or further enquiries to APoGI@chime.ucl.ac.uk or the APoGI Contacts