APoGI for the Haemoglobin Disorders

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Implications for a Child when One Partner carries Alpha Zero Thalassaemia and the Other carries Alpha Plus Thalassaemia

This couple could have a child with haemoglobin H disease.

Partner who carries alpha zero thalassaemia Partner who carries alpha plus thalassaemia
Not a carrier Carrier of alpha zero thalassaemia Carrier of alpha plus thalassaemia Child with "haemoglobin H disease"

In each pregnancy, there are four possibilites:

Haemoglobin H disease...

... is a moderate form of anaemia. It is unfortunate that doctors call it a disease, because most people with haemoglobin H disease lead a normal life. They go to school, work and have children just like other people. They occasionally need additional medical treatment, and should attend a haematology clinic every year for a check-up.

This couple should see a specialist in haemoglobin disorders for expert information. Once they have seen a specialist most couples are not worried about the possibility of having a child with haemoglobin H disease. They usually ask for the baby to be checked when it is born, to see if it has Haemoglobin H disease or not.

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These documents are part of the APoGI May 1998 (Evaluation) Release and are made available subject to the APoGI Disclaimers covering usage, distribution and copying.

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